Thermo Fisher Scientific NTRK2 Monoclonal Antibody (OTI2E1), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

NTRK2 (TRKB) encodes a receptor belonging to the neurotrophic factor family, essential for the development and maintenance of the mammalian nervous system.
It serves as the receptor for brain-derived neurotrophic factor (BDNF), regulating short-term synaptic functions and long-term potentiation of brain synapses.
TrkB is a membrane-bound tyrosine kinase involved in neural differentiation and signaling via the MAPK pathway.
Mutations in the TrkB gene are associated with obesity and mood disorders.
Alternative splice variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.