Thermo Fisher Scientific CXCL13/BCA1 Polyclonal Antibody
CXCL13/BCA1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등에 사용 가능. Human과 Mouse 시료에 반응하며, Protein A로 정제된 고순도 항체. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CXCL13 (amino acids 23–109) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CXCL13 (also known as BCA-1 and Angie) is a small chemokine strongly expressed in secondary lymphoid organs. It promotes the migration of B lymphocytes (B-1 and B-2) to the follicles of the spleen, lymph nodes, and Peyer’s patches. CXCL13 is produced by macrophages, including large peritoneal macrophages, Kupffer cells, and lung macrophages. The cellular ligand for CXCL13 is CXCR5 (also known as BLR-1), which is expressed on B cells, Tfh cells, and some memory T cells. CXCL13 plays a role in chronic lymphocytic leukemia (CCL) and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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