Thermo Fisher Scientific CXCL11 Polyclonal Antibody
CXCL11 단백질을 인식하는 토끼 폴리클로날 항체로, Mouse 및 Rat 시료에서 반응합니다. IHC, ICC/IF, ELISA 등 다양한 실험에 사용 가능하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. -20°C 보관, 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse CXCL11 (amino acids 22–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4), with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interferon-inducible T-cell alpha chemoattractant (I-TAC), also known as CXCL11 or IP-9, belongs to the CXC chemokine family. It is expressed in peripheral blood leukocytes, pancreas, liver, thymus, spleen, lung, small intestine, placenta, and prostate, with a molecular weight of 8–11 kDa.
CXCL11 regulates calcium release and induces chemotactic responses in activated T-cells, serving as a dominant ligand for the CXC receptor-3.
The gene encoding this protein contains four exons and multiple polyadenylation signals, suggesting cell-specific expression regulation. IFN-γ strongly induces its transcription, and it is upregulated in patients with AIDS, dementia, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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