Thermo Fisher Scientific LRRTM1 Monoclonal Antibody (OTI5H9), TrueMAB
인체 LRRTM1 단백질을 인식하는 단클론 항체로, WB 및 IHC(P) 적용 가능. 고순도 친화 크로마토그래피 정제, 보존제 무첨가. 연구용으로 신경계 관련 단백질 발현 연구에 적합.
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Thermo Fisher Scientific LRRTM1 Monoclonal Antibody (OTI5H9), TrueMAB
Applications and Tested Dilutions
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 182-422 of human LRRTM1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and play key roles in presynaptic and postsynaptic glutamatergic differentiation. LRRTM1 and LRRTM2 are particularly potent in inducing presynaptic differentiation.
Each LRRTM protein is a type I transmembrane protein with ten extracellular leucine-rich repeats and a short intracellular tail, exhibiting distinct developmental expression patterns.
LRRTM1 is a maternally suppressed gene associated paternally with handedness and schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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