Thermo Fisher Scientific LRRTM1 Monoclonal Antibody (OTI5H9), TrueMAB

Thermo Fisher Scientific LRRTM1 Monoclonal Antibody (OTI5H9), TrueMAB

Applications and Tested Dilutions

• Western Blot (WB): 1:2,000
• Immunohistochemistry (Paraffin) (IHC-P): 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and play key roles in presynaptic and postsynaptic glutamatergic differentiation. LRRTM1 and LRRTM2 are particularly potent in inducing presynaptic differentiation.
Each LRRTM protein is a type I transmembrane protein with ten extracellular leucine-rich repeats and a short intracellular tail, exhibiting distinct developmental expression patterns.
LRRTM1 is a maternally suppressed gene associated paternally with handedness and schizophrenia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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