Thermo Fisher Scientific CYP1B1 Monoclonal Antibody (2F8)

Applications

Tested Dilution

Publications

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

2F8

Immunogen

CYP1B1 (NP_000095, 453 a.a. approximately 542 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYP1B1,uniProtId:Q16678-1,ncbiNodeId:9606,antigenRange:453-542,antigenLength:543,antigenImageFileName:H00001545-M03_CYP1B1_Q16678-1_House_mouse.svg,antigenImageFileNamePDP:H00001545-M03_CYP1B1_Q16678-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: NKDLTSRVMI FSVGKRRCIG EELSKMQLFL FISILAHQCD FRANPNEPAK MNFSYGLTIK PKSFKVNVTL RESMELLDSA VQNLQAKETC

Target Information

CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 super family of enzymes which are monooxygenases and it catalyzes many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol and is also involved in the metabolism of substances active in the eye growth and differentiation and hence plays a putative role in ocular development. Mutated proteins are known to cause primary congenital glaucoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.