Thermo Fisher Scientific CYLD Monoclonal Antibody (2C3)
CYLD 단백질을 인식하는 Mouse monoclonal 항체(클론 2C3)로, Human 시료에 반응합니다. ICC/IF 및 ELISA에 사용 가능하며, Affinity chromatography로 정제된 액상 형태입니다. CYLD 신호전달 연구 및 종양 억제 단백질 분석에 적합합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C3 |
| Immunogen | CYLD (AAH12342, 854 a.a. ~ 953 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QNMELFAVLC IETSHYVAFV KYGKDDSAWL FFDSMADRDG GQNGFNIPQV TPCPEVGEYL KMSLEDLHSL DSRRIQGCAR RLLCDAYMCM YQSPTMSLYK
Target Information
CYLD is a 956 amino acid cytoplasmic deubiquitinating enzyme belonging to the ubiquitin carboxy-terminal hydrolases (UCH) family. It contains three CAP-GLY domains, a proline-rich region, a SH3 binding domain, and a catalytic domain homologous to UCH.
CYLD acts as a tumor suppressor protein affecting the JNK signaling pathway, and negatively regulates TRAF2 and NF-kappa-B signaling. It also regulates the I-kappa-B kinase pathway and exhibits deubiquitinating activity toward non-Lys-48-linked polyubiquitin chains. TRAP1 is a novel substrate for CYLD deubiquitination.
Mutations in CYLD are associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific CYP1B1 Monoclonal Antibody (2F8)
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CYLD Monoclonal Antibody (2F9)
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CYLD Monoclonal Antibody (2C3)
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CYLC1 Monoclonal Antibody (6F12)
570,400원
Thermo Fisher Scientific
Thermo Fisher Scientific CYLD Monoclonal Antibody (2G1)
518,100원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|