Thermo Fisher Scientific F4/80 Chimeric Recombinant Rabbit Monoclonal Antibody (Cl:A3-1)
마우스 F4/80 항원을 인식하는 키메릭 재조합 래빗 단클론 항체로, IHC 및 유세포분석에 적합합니다. 고순도 Protein A 정제, 1 mg/mL 농도의 액상 형태이며, 단기 4°C 보관 및 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Cl:A3-1 |
| Immunogen | Thioglycollate-stimulated peritoneal macrophages of mouse origin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074212 |
Product Specific Information
This antibody recognizes the mouse F4/80 antigen, a 160 kDa glycoprotein expressed by murine macrophages.
Target Information
F4/80 antigen is a 160 kDa cell surface glycoprotein, a member of the EGF TM7 family of proteins, sharing 68% amino acid identity with human EMR1. Expression varies during macrophage maturation and activation. It is expressed on various mature tissue macrophages including Kupffer cells, Langerhans cells, microglia, and macrophages in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma, and spleen red pulp. Expression may also occur on some dendritic cells but is absent in macrophages located in T cell areas of spleen and lymph nodes. The ligands and biological roles of F4/80 remain under study, with evidence suggesting involvement in efferent CD8⁺ regulatory T cell generation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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