Thermo Fisher Scientific SUR2A Monoclonal Antibody (N319A/14), APC
SUR2A 단백질을 인식하는 APC 결합 단클론 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC에 사용 가능하며, 120kDa SUR2A 검출에 특이적입니다. Protein G 정제, 액상 형태로 보존하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific SUR2A Monoclonal Antibody (N319A/14), APC
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N319A/14 |
| Immunogen | Fusion protein amino acids 1505–1546 (SSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK, cytoplasmic C-terminus) of mouse SUR2A |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932061 |
Additional Formats
- Unconjugated (MA5-27637)
- FITC (MA5-45608)
- PE (MA5-45610)
- PerCP (MA5-45609)
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45607 detects SUR2A in 20 µg of mouse brain membrane lysate using colorimetric immunoblot with goat anti-mouse IgG:HRP secondary antibody.
- Detects approximately 120 kDa.
- Does not cross-react with SUR2B.
- Formerly sold as clone S319A-14.
Target Information
Sulfonylurea receptors (SUR) are membrane proteins that serve as molecular targets of sulfonylurea anti-diabetic drugs, which promote insulin release from pancreatic beta cells. SUR proteins are subunits of inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2). Four Kir6.x and four SUR subunits form the KATP channel, which monitors cellular energy balance by sensing ATP and ADP levels and regulating channel opening and closing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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