Thermo Fisher Scientific SUR2A Monoclonal Antibody (N319A/14), PE
SUR2A 단백질을 특이적으로 인식하는 Thermo Fisher Scientific의 단클론 항체. PE로 결합되어 형광 분석에 적합하며, WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. 사람, 마우스, 랫트 반응성. 단백질 G 정제, 보존제 없음, 4°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | — |
| Immunohistochemistry (IHC) | Assay-dependent | — |
| Immunocytochemistry (ICC/IF) | Assay-dependent | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N319A/14 |
| Immunogen | Fusion protein amino acids 1505–1546 (SSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK, cytoplasmic C-terminus) of mouse SUR2A |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932064 |
Available Formats
- Unconjugated (MA5-27637)
- APC (MA5-45607)
- FITC (MA5-45608)
- PerCP (MA5-45609)
- Request custom conjugation
Product Specific Information
- 1 µg/mL of MA5-45610 was sufficient for detection of SUR2A in 20 µg of mouse brain membrane lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 120 kDa.
- Does not cross-react with SUR2B.
- This antibody was formerly sold as clone S319A-14.
Target Information
Sulfonylurea receptors (SUR) are membrane proteins targeted by sulfonylurea class anti-diabetic drugs that promote insulin release from pancreatic beta cells. SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2). Four Kir6.x and four SUR subunits form the KATP channel, which regulates cellular energy balance by sensing intracellular ATP and ADP levels and controlling potassium ion flow accordingly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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