Thermo Fisher Scientific SOCS2 Polyclonal Antibody
SOCS2 단백질의 C-말단 합성 펩타이드를 면역원으로 제작된 Rabbit Polyclonal Antibody. WB 및 IHC(P) 응용에 적합하며, Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of SOCS-2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Heart, placenta, lung, kidney
- Cellular location: Cytoplasm and membrane
Target Information
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling.
The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, and interferon (IFN)-gamma.
The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and is thought to be involved in regulation of IGF1R-mediated cell signaling.
Knockout studies in mice suggest a regulatory role of this gene in IGF-1 related growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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