Thermo Fisher Scientific Phospho-PDGFRB (Tyr1009) Polyclonal Antibody
PDGFRB (Tyr1009) 인산화 형태를 인식하는 rabbit polyclonal antibody. Western blot에 적합하며 Human, Mouse에 반응. 항원 친화 정제 및 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide corresponding to residues around human PDGF Receptor beta (phospho Tyr1009). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.78 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792934 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%)
- Positive Control: PDGF-treated NIH-3T3
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
PDGFRB is a receptor tyrosine kinase implicated in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for cells of mesenchymal origin. The ligand identity determines whether the receptor forms a homodimer or heterodimer (PDGF receptor alpha and beta). The PDGFRB gene is located on chromosome 5, near GM-CSF and CSF1R genes, all implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB (CD140b) and ETV6 is associated with chronic myeloproliferative disorder with eosinophilia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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