Thermo Fisher Scientific Interferon alpha-2 (IFNA2) Monoclonal Antibody (N27)
인간 IFN alpha-2를 인식하는 마우스 단클론 항체로, ICC/IF, Flow Cytometry, ELISA 및 Blocking Assay에 사용 가능. 단백질 A/G로 정제된 액상 형태이며 PBS(pH 7.4) 버퍼에 보존제 없이 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Blocking Assay | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N27 |
| Immunogen | Purified recombinant human IFN-alpha2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interferon alpha (IFN-α) is a Type I interferon belonging to a family of structurally related, species-specific proteins found only in vertebrates. Interaction of IFN-α with its receptor activates multiple signaling pathways involved in the innate immune response against viral infection. In humans, the IFN-α gene cluster is located on chromosome 9 and includes 14 alpha isoforms, along with single beta, omega, epsilon, and kappa isoforms. Homologous molecules exist in many species including rodents, birds, reptiles, and fish. IFN-α is primarily produced by plasmacytoid dendritic cells and plays a critical role in antiviral defense and immune modulation. Dysregulation of IFN-α activity has been associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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