Thermo Fisher Scientific PDE1A Monoclonal Antibody (OTI5H4), TrueMAB
PDE1A 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 적합합니다. Human 유래 항원으로 제작되었으며, Lyophilized 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 및 PBS 완충용액에 보존되어 있습니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 259–545 of human PDE1A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide levels by hydrolyzing cAMP and/or cGMP to their respective nucleoside 5′-monophosphates.
Members of the PDE1 family, including PDE1A, are Ca²⁺/calmodulin-dependent enzymes activated by calmodulin in the presence of Ca²⁺ (Michibata et al., 2001).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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