Thermo Fisher Scientific PDE1A Monoclonal Antibody (OTI7D5), TrueMAB
PDE1A 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot 및 IHC(P)에서 검증됨. 인간 시료 반응성, Mouse IgG2a 아이소타입. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 259-545 of human PDE1A produced in E.coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5′-monophosphates. Members of the PDE1 family, such as PDE1A, are Ca²⁺/calmodulin-dependent enzymes that are activated by calmodulin in the presence of Ca²⁺ (Michibata et al., 2001).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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