Thermo Fisher Scientific Calbindin 1 (CALB1) Monoclonal Antibody (rCALB1/8499)
Calbindin 1(CALB1)을 인식하는 mouse monoclonal antibody로, IHC(P) 및 IHC(PFA) 실험에 적합합니다. 인간 시료에 반응하며, Protein A/G로 정제된 액상 형태입니다. 4°C 보관, 동결 금지. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rCALB1/8499 |
| Immunogen | Recombinant fragment (around aa 7–96) of human CALB1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin) is a highly conserved 28kDa calcium-binding protein with broad tissue distribution. It belongs to the family of low molecular weight calcium-binding proteins (CaBPs), including calmodulin, S-100, parvalbumin, and troponin C. These CaBPs share homologous EF-hand motifs responsible for Ca²⁺ binding.
Calbindin-D-28K is predominantly expressed in subpopulations of neurons in the central and peripheral nervous systems and in epithelial cells involved in Ca²⁺ transport, such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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