Thermo Fisher Scientific APC13 Polyclonal Antibody
APC13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 세포주기 관련 단백질 연구용으로 적합.
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Thermo Fisher Scientific APC13 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the center of human APC13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months; for long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11156027 |
Product Specific Information
- Suggested positive control: Jurkat cell lysate
- PA5-20956 can be used with blocking peptide PEP-1070
Target Information
Cell cycle-regulated protein ubiquitination and degradation within subcellular domains are essential for normal mitosis progression.
APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase controlling progression through mitosis and the G1 phase.
APC/C degrades anaphase inhibitors, mitotic cyclins, and spindle-associated proteins, ensuring proper mitotic sequence.
APC13 promotes stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C complex.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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