Thermo Fisher Scientific SUMO-3 Polyclonal Antibody
Western blot과 IHC에 사용 가능한 rabbit polyclonal 항체로, Human, Mouse, Rat에 반응합니다. SUMO-3 단백질을 인식하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 2–8°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide near the carboxy terminus of human SUMO3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157423 |
Product Specific Information
- A suggested positive control is mouse liver tissue lysate.
- PA5-20960 can be used with blocking peptide PEP-1074.
Target Information
Small ubiquitin-related modifier (SUMO) proteins are members of the ubiquitin-like protein family.
SUMO-3 regulates amyloid beta generation and may be critical in the onset or progression of Alzheimer’s disease.
SUMO-2/3 forms poly-SUMO chains, and SUMO-1, 2, and 3 proteins localize to the nuclear membrane, nuclear bodies, and cytoplasm, respectively.
SUMOylation is essential for mammalian cell cycle regulation. SUMO-2/3 localizes to centromeres and condensed chromosomes where it binds CENP-E.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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