Thermo Fisher Scientific RAGE Polyclonal Antibody
RAGE 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Mouse 및 Rat 시료에서 Western blot과 IHC에 검증됨. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA1075
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific RAGE Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 10 publications |
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1–2 µg/mL | View 1 publication |
| Neutralization (Neu) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides corresponding to residues C(362) W R K R Q P R (R/L) E E R K A P E S Q E D(380) of rat RAGE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2269243 |
Product Specific Information
PA1-075 detects receptor for advanced glycation endproducts (RAGE) from mouse and rat samples.
It has been successfully used in Western blot and immunohistochemistry procedures.
By Western blot, this antibody detects two bands in the 45 kDa range representing the RAGE protein pre and post-glycosylation in mouse lung extract.
It also detects an ~25 kDa protein believed to be a proteolytic degradation product.
Immunohistochemical staining of RAGE in transgenic mouse retina results in staining of the retinal pigmented epithelium and photoreceptor cell layers.
The PA1-075 immunogen is a synthetic peptide corresponding to residues C(362) W R K R Q P R (R/L) E E R K A P E S Q E D(380) of rat RAGE.
This sequence is 100% conserved in mouse and 70% conserved in humans.
This peptide (Cat. # PEP-194) is available for use in neutralization and control experiments.
Target Information
Able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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