Thermo Fisher Scientific THNSL2 Polyclonal Antibody
THNSL2 단백질을 인식하는 염소 유래 폴리클로날 항체로, WB 및 IHC(P) 실험에 적합합니다. 인체 반응성이 확인되었으며, 고순도(암모늄 황산 침전)로 정제된 액상 형태 제품입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific THNSL2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-EGNSDELDEPIKT (aa192–204 of THNSL2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554558 |
Product Specific Information
- Predicted to react with cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
THNSL2 (threonine synthase-like 2), also known as TSH2, is a 484 amino acid protein belonging to the threonine synthase family. Utilizing pyridoxal phosphate as a cofactor, THNSL2 may function as a catabolic phospholyase on gamma and beta phosphorylated substrates.
It may also degrade O-phospho-threonine to alpha-ketobutyrate, ammonia, and phosphate.
Existing as four alternatively spliced isoforms, THNSL2 is encoded by a gene mapping to human chromosome 2p11.2.
Chromosome 2 comprises approximately 8% of the human genome, encoding over 1,400 genes.
Several genetic diseases are linked to genes on chromosome 2, including:
- Harlequin ichthyosis (ABCA12 mutation)
- Sitosterolemia (ABCG5/ABCG8 defects)
- Alstrom syndrome (ALMS1 mutation)
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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