Thermo Fisher Scientific HDAC8 Recombinant Rabbit Monoclonal Antibody (SD082-07)
HDAC8 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 유세포분석에 적합합니다. 높은 특이성과 일관된 로트 간 품질을 제공하며, HEK293 세포에서 발현된 동물 유래 성분이 없는 포뮬레이션입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD082-07 |
| Immunogen | Synthetic peptide within Human HDAC8 (aa 61–110) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809689 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal production clones.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
HDAC8 (Histone Deacetylase 8) participates in chromatin remodeling and transcriptional regulation.
Histone acetylation alters nucleosomal conformation, increasing DNA accessibility to transcription factors, while deacetylation is associated with transcriptional silencing.
HDAC8, isolated from human kidney, is localized in the nucleus and contributes to tissue development and cancer etiology.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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