Thermo Fisher Scientific HSPA14 Recombinant Rabbit Monoclonal Antibody (SD08-48)
HSPA14 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 높은 특이성과 일관성을 제공하며, HEK293 세포에서 발현된 동물 유래 성분 없는 포뮬레이션입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD08-48 |
| Immunogen | Synthetic peptide within Human HSPA14 aa 51–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809691 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Heat shock proteins (HSPs) are highly conserved and abundantly expressed proteins with diverse functions such as protein complex assembly, membrane transport of nascent peptides, and protein folding regulation.
HSPA14 (Heat Shock 70kDa Protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid protein derived from human dendritic cells. It belongs to the heat shock protein 70 family and is believed to promote dendritic cell maturation.
HSPA14 may also stimulate secretion of proinflammatory cytokines including IL-12p70, IL-1β, TNFα, and chemokines IP-10, MIP-1α, MIP-1β, and RANTES.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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