Thermo Fisher Scientific PAX6 Recombinant Rabbit Monoclonal Antibody (SD08-31)
PAX6 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC/IF에 적합. HEK293 발현 시스템 사용으로 높은 특이성과 재현성 제공. Protein A로 정제된 액상 항체이며, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD08-31 |
| Immunogen | Recombinant protein within Human PAX6 aa 152–351 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809687 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The PAX6 gene encodes paired box gene 6, a human homolog of the Drosophila melanogaster gene prd. This protein contains both a paired box domain and a homeobox domain, which bind DNA and act as transcriptional regulators.
PAX6 is expressed in the developing nervous system and eyes. Mutations in this gene are associated with ocular disorders such as aniridia and Peter’s anomaly. Alternatively spliced transcript variants encoding different isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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