Thermo Fisher Scientific SHP2 Polyclonal Antibody
SHP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제, 1 mg/mL 농도. 연구용으로 세포 신호 조절 및 질병 관련 연구에 활용 가능.
- 카탈로그번호
- PA520278
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide from near the carboxy terminus of human SHP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151829 |
Product Specific Information
- A suggested positive control is mouse skeletal muscle tissue lysate.
- PA5-20278 can be used with blocking peptide PEP-0408.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.
PTPs are signaling molecules that regulate cellular processes including growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains that mediate phospho-tyrosine binding and substrate interaction.
It is widely expressed and plays a regulatory role in diverse signaling events such as mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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