Thermo Fisher Scientific VIM Monoclonal Antibody (OTI5C10), TrueMAB
Vimentin 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC에 적합. Human 시료 반응성. Affinity chromatography로 정제된 1 mg/mL 액상 시약. 연구용 전용, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:150 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C10 |
| Immunogen | Full length human recombinant protein of human VIM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats:
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular protein transport between the nucleus and plasma membrane. Unlike other IFPs, vimentin is co-expressed with desmin during early cellular development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by storing cholesterol-containing lipid droplets and is regulated by phosphorylation, which induces cytoskeletal rearrangements that facilitate cholesterol transport to mitochondria, enhancing steroidogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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