Thermo Fisher Scientific VIM Monoclonal Antibody (OTI1D3), TrueMAB
인간 Vimentin 단백질을 인식하는 마우스 단클론 항체. Western blot에 최적화된 TrueMAB 형식. 액상 형태로 1 mg/mL 농도 제공. PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D3 |
| Immunogen | Full length human recombinant protein of human VIM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular transport of proteins between the nucleus and plasma membrane. Vimentin is co-expressed with desmin during early cellular development and later replaced by tissue-specific IFPs. It also plays a role in steroid synthesis by regulating cholesterol-containing lipid droplets. Phosphorylation of vimentin by protein kinase leads to cytoskeletal rearrangements that facilitate cholesterol transport to mitochondria, enhancing steroid production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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