Thermo Fisher Scientific ALK Monoclonal Antibody (OTI9H5), TrueMAB
인간 ALK 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot에 최적화되어 있습니다. 뇌 발달 관련 연구 및 종양에서의 ALK 변이 분석에 활용됩니다. 액상 형태로 제공되며, -20°C에서 안정적으로 보관 가능합니다.
- 카탈로그번호
- TA801325
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9H5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1300–1620 of human ALK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily and plays a vital role in brain development. Mutations, rearrangements, and amplifications in the ALK gene are associated with tumors such as anaplastic large cell lymphoma, neuroblastoma, and non-small cell lung cancer. Chromosomal rearrangements often generate a fusion gene between ALK and nucleophosmin (NPM), producing an oncogenic NPM-ALK protein. ALK encodes a receptor tyrosine kinase with transmembrane and extracellular domains, showing high sequence similarity to LTK. It is essential for neuronal development and function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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