Thermo Fisher Scientific TRIM5 alpha Polyclonal Antibody
TRIM5 alpha 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC에 사용 가능. Human 및 Rhesus monkey 반응성. 항원 친화 크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (IHC) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rhesus monkey |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids near the mid-region of rhesus monkey TRIM5 alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155842 |
Product Specific Information
- In Western blot applications, this antibody detects a band at approximately 55 kDa.
- Suggested positive control: human stomach tissue lysate.
- PA5-20051 can be used with blocking peptide PEP-0170.
Target Information
The protein encoded by this gene is a member of the tripartite motif (TRIM) family.
The TRIM motif includes three zinc-binding domains (a RING, a B-box type 1, and a B-box type 2) and a coiled-coil region.
This protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies.
It functions as an E3 ubiquitin-ligase and ubiquitinates itself to regulate subcellular localization.
It may play a role in retroviral restriction.
Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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