Thermo Fisher Scientific Parkin Polyclonal Antibody, Biotin
Rabbit polyclonal antibody recognizing human Parkin protein, biotin-conjugated for enhanced assay versatility. Validated for WB, ELISA, and IP applications. Suitable for research on Parkinson’s disease mechanisms. For research use only.
- 카탈로그번호
- PARK-BIOTIN
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 390–440 on human Parkin protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson’s disease and autosomal recessive juvenile Parkinson’s disease. Alternative splicing produces multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but currently lack transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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