Thermo Fisher Scientific Parkin Polyclonal Antibody, FITC
Parkin 단백질을 인식하는 FITC 결합 토끼 폴리클로날 항체로, WB, ELISA, IP 등 다양한 응용에 사용 가능. 인간 Parkin(aa 390-440) 펩타이드로 면역화됨. 형광 특성(Excitation/Emission: 498/517 nm) 보유. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 390–440 on human Parkin protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation.
Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease.
Alternative splicing produces multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but currently lack transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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