Thermo Fisher Scientific KCNMB4 Polyclonal Antibody
KCNMB4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 적합합니다. 인간, 마우스, 랫드, 영장류 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
- 카탈로그번호
- PA5103146
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCNMB4 (Accession Q86W47), corresponding to amino acid residues R97–T147 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852516 |
Product Specific Information
Antibody detects endogenous levels of total MaxiK beta.
Target Information
MaxiK channels are large conductance, voltage- and calcium-sensitive potassium channels fundamental to the control of smooth muscle tone and neuronal excitability. They consist of two subunits: the pore-forming alpha subunit and the modulatory beta subunit. The KCNMB4-encoded protein acts as an auxiliary beta subunit, slowing activation kinetics, increasing calcium sensitivity, and shifting the voltage range of activation to more negative potentials compared to the beta 1 subunit.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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