Thermo Fisher Scientific HLA-G Polyclonal Antibody
Rabbit polyclonal antibody against human HLA-G protein. Validated for Western blot with high specificity. Supplied as a liquid form in PBS with glycerol. Suitable for research use in immunology and immunopeptidomics studies.
- 카탈로그번호
- PA5103139
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HLA-G (Accession P17693), corresponding to amino acid residues L148–N198 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852509 |
Product Specific Information
This antibody detects endogenous levels of total HLA-G.
Target Information
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin).
The heavy chain is anchored in the membrane and is approximately 45 kDa. The gene contains 8 exons:
- Exon 1 encodes the leader peptide
- Exons 2 and 3 encode the α1 and α2 domains (peptide-binding)
- Exon 4 encodes the α3 domain
- Exon 5 encodes the transmembrane region
- Exon 6 encodes the cytoplasmic tail
HLA-G is expressed on fetal-derived placental cells.
HLA and MHC antibodies are important tools in immunopeptidomics, enabling identification and characterization of neoantigens via high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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