Thermo Fisher Scientific ALKBH3 Polyclonal Antibody
Thermo Fisher Scientific의 ALKBH3 Polyclonal Antibody는 Human, Mouse, Rat 시료에 반응하며 Western blot에 적합합니다. Rabbit에서 유래한 비결합 항체로, 항원 친화 크로마토그래피로 정제되었습니다. ALKBH3 단백질 연구용으로 높은 특이성과 재현성을 제공합니다.
- 카탈로그번호
- PA576827
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human ALKBH3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720554 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate, and iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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