Thermo Fisher Scientific EPC1 Polyclonal Antibody
EPC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunocytochemistry에 사용 가능. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 보유. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human EPC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720553 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex, which is involved in transcriptional activation of select genes primarily through acetylation of nucleosomal histones H4 and H2A. This modification may alter nucleosome–DNA interactions and enhance the binding of modified histones with other transcription-regulating proteins. The NuA4 complex is associated with processes such as oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest, replicative senescence, apoptosis, and DNA repair. It may also play a direct role in DNA repair when recruited to sites of DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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