Thermo Fisher Scientific CCR7 Polyclonal Antibody
Thermo Fisher Scientific의 CCR7 Polyclonal Antibody는 인간 CCR7 단백질을 인식하는 Rabbit IgG 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.02% sodium azide를 포함한 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7 (amino acids 180–230). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890286 |
Product Specific Information
Positive controls that may be used include:
- Human Spleen Tissue Lysate
- Human Spleen Tissue Slide
Target Information
CCR7 is a member of the G protein-coupled receptor family, which is a subfamily of chemokines. CCR7 was identified to be induced by Epstein–Barr virus (EBV) and is thought to mediate EBV effects on B lymphocytes. It is expressed in blood, bone marrow, lymph node, and intestine, particularly in lymphoid tissues and activated B and T lymphocytes. CCR7 controls the migration of memory T cells to inflamed tissues and stimulates dendritic cell maturation. The chemokine ligand CCL19 (ECL) is a specific ligand of this receptor. Receptors for the C–C chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5, and the Duffy blood group antigen, which are important in T cell chemotaxis and migration of phagocytic cells to inflammation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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