Thermo Fisher Scientific RPSA Polyclonal Antibody
RPSA 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 완충액에 보관되며, 4°C 단기 및 -20°C 장기 보관 권장.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA. The immunogen is located within amino acids 190–240 of RPSA. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890406 |
Product Specific Information
Positive controls that may be used include: Caco-2 Cell Lysate
Target Information
Laminins are extracellular matrix glycoproteins that form a major component of basement membranes. They are involved in processes such as cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Their effects are mediated through interactions with cell surface receptors, including integrins and non-integrin laminin-binding proteins.
The RPSA gene encodes a high-affinity laminin receptor (also known as 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP), or p40 ribosome-associated protein). This receptor is evolutionarily conserved and plays a key biological role. Increased expression has been observed in colon carcinoma and lung cancer cell lines, correlating with invasive and metastatic potential. Multiple pseudogene copies exist, likely derived from retropositional events. Two alternatively spliced transcript variants encoding the same protein are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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