Thermo Fisher Scientific CXCR5 Polyclonal Antibody
CXCR5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 최적화됨. B세포 이동 연구에 활용 가능하며, 0.5 mg/mL 농도의 액상 형태로 제공. 단기 보관은 4°C, 장기 보관은 -20°C 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
- Suggested positive control: A375 or Daudi
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 20–32 of human CXCR5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2230325 |
Target Information
CXCR5 (C-X-Chemokine Receptor Type 5, CD185), also known as Burkitt lymphoma receptor 1 (BLR1), belongs to the CXC chemokine receptor family.
It is a G protein-coupled seven transmembrane receptor for chemokine BLC and is specifically expressed in Burkitt’s lymphoma and lymphatic tissues such as lymph node follicles and spleen.
CXCR5 plays an essential role in B cell migration and has been reported in various tissues including blood, salivary gland, lymphatic organs, bone marrow, brain, liver, skin, spleen, stomach, and tonsil.
G-protein Coupled Receptors (GPCRs) share a structural motif of seven membrane-spanning helices and exist in both active and inactive forms.
Their regulation and signaling mechanisms are critical for cellular physiology and pharmacological research, with GPCR-targeted drugs such as Zyprexa and Claritin demonstrating their biomedical importance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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