Thermo Fisher Scientific OSBPL2 Monoclonal Antibody (OTI2E6), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

This gene encodes a member of the oxysterol-binding protein (OSBP) family, which are intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a conserved C-terminal OSBP-like sterol-binding domain.
The encoded OSBPL2 protein contains only the sterol-binding domain and associates with the Golgi apparatus. It binds strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but not to 25-hydroxycholesterol.
Transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.