Thermo Fisher Scientific HBS1L Monoclonal Antibody (OTI1C1), TrueMAB
HBS1L 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 IHC(Paraffin)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. 1 mg/mL 농도, PBS buffer(8% trehalose) 포함, 보존제 없음. -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human HBS1L produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The HBS1L gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues, with the highest levels in heart and skeletal muscle.
The intergenic region between this gene and the MYB gene is a quantitative trait locus (QTL) influencing fetal hemoglobin levels and affecting erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content.
DNA polymorphisms in this region are associated with fetal hemoglobin levels and pain crises in sickle cell disease.
A single nucleotide polymorphism in exon 1 of this gene is significantly associated with disease severity in beta-thalassemia/Hemoglobin E.
Multiple alternatively spliced transcript variants encoding different protein isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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