Thermo Fisher Scientific GPNMB Monoclonal Antibody (OTI5C2), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The GPNMB gene encodes a type I transmembrane glycoprotein homologous to the melanocyte-specific pMEL17 precursor.
GPNMB is expressed in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic lines.
It may play a role in growth delay and reduction of metastatic potential.
Two transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.