Thermo Fisher Scientific CRP Monoclonal Antibody (OTI6F3), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CRP (C-reactive protein) is a major cyclic, pentameric acute-phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids with a molecular weight of approximately 24 kDa.
Produced by the liver, CRP levels rise sharply during inflammation, infection, or injury (up to 100–1000 fold). It initiates the classical complement cascade, binds nuclear components such as chromatin and histones, and plays a key role in innate immunity.
CRP acts as an opsonin, activating monocytes/macrophages and participating in pathogen clearance. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.