Thermo Fisher Scientific Cytochrome P450 Reductase Recombinant Rabbit Monoclonal Antibody (9U1U7)
Cytochrome P450 Reductase를 인식하는 토끼 유래 재조합 단클론 항체로, WB, IHC, ICC, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 높은 특이성과 재현성을 제공합니다. 연구용으로 ER 막 단백질 검출에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9U1U7 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 100–200 of human CYPOR (P16435) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912011 |
Product Specific Information
Positive test controls include: HeLa, A-549, Mouse lung, Mouse liver, Mouse brain, Rat liver.
The target is usually found in the following locations: Endoplasmic reticulum membrane, Peripheral membrane protein.
Immunogen sequence:
KDAHRYGMRG MSADPEEYDL ADLSSLPEID NALVVFCMAT YGEGDPTDNA QDFYDWLQET DVDLSGVKFA VFGLGNKTYE HFNAMGKYVD KRLEQLGAQR I
Target Information
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes.
Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia, and Antley-Bixler syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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