
Thermo Fisher Scientific MCP-1 Monoclonal Antibody (23007)
인간 MCP-1을 인식하는 Mouse IgG2b 단일클론 항체로, WB, IHC, ELISA, Neutralization에 적합합니다. E. coli 유래 recombinant human CCL2/JE/MCP-1을 면역원으로 사용하며, 교차반응이 거의 없습니다. 단백질 A/G로 정제된 동결건조 형태로 연구용에 적합합니다.
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Thermo Fisher Scientific MCP-1 Monoclonal Antibody (Clone 23007)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5–15 µg/mL |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 2–8 µg/mL |
| Neutralization (Neu) | 0.5–2.0 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 23007 |
| Immunogen | E. coli-derived recombinant human CCL2/JE/MCP-1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609450 |
Product Specific Information
- In ELISAs, this antibody does not cross-react with recombinant mouse CCL2, 3, 4, rhCCL3, 4, 5, 7, or 8.
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody (LAL method).
Target Information
This gene encodes a cytokine belonging to the CC subfamily involved in immunoregulatory and inflammatory processes. The protein shows chemotactic activity for monocytes and basophils, but not for neutrophils or eosinophils. It is implicated in diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. MCP-1 binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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