Thermo Fisher Scientific CCL5 (RANTES) Monoclonal Antibody (21418)
Thermo Fisher Scientific의 CCL5 (RANTES) Monoclonal Antibody (Clone 21418)는 인간 및 비인간 영장류 반응성을 가지며, ELISA, Western blot, Neutralization에 적합합니다. E. coli 유래 재조합 인간 CCL5로 면역화된 단일클론 항체로, 높은 특이성과 낮은 엔도톡신 수준을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 2–8 µg/mL |
| Neutralization (Neu) | 0.04–0.12 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 21418 |
| Immunogen | E. coli-derived recombinant human CCL5/RANTES |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609446 |
Product Specific Information
When used in combination with the biotinylated anti-human CCL5/RANTES detection antibody in sandwich ELISAs, no significant cross-reactivity or interference is observed with recombinant human or animal cytokines and growth factors, including ANG, CNTF, EGF, FGF, GM-CSF, IL series, MCP-1, MIP, PDGF, SCF, SLPI, TGF, TNF, and others.
Reconstitute at 0.5 mg/mL in sterile PBS.
Endotoxin level is <0.10 EU per 1 µg of antibody by the LAL method.
Target Information
CCL5 (RANTES) is a chemokine gene located on chromosome 17q. It belongs to the CC subfamily and acts as a chemoattractant for monocytes, memory T helper cells, and eosinophils.
CCL5 induces histamine release from basophils, activates eosinophils, and functions as a natural ligand for CCR5, suppressing replication of HIV-1 R5 strains in vitro.
Alternative splicing leads to multiple transcript variants encoding different isoforms.
Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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