
Thermo Fisher Scientific DEC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DEC1 (BHLHE40) region 350–412. Validated for WB, IHC(P), and IP. Unconjugated liquid form, 1 mg/mL concentration. Recommended storage at 4 °C, shipped on wet ice. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 350 and the C‑terminus (residue 412) of human Differentially Expressed in Chondrocytes (Basic Helix‑Loop‑Helix Domain Containing, Class B, 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with Tris‑EDTA pH 9.0 is recommended for FFPE tissue sections
- Based on 100 % sequence identity, this antibody is predicted to react with Orangutan
Target Information
Differentiated embryo‑chondrocyte expressed gene 1 (DEC1) is an important protein involved in embryonic cell differentiation, proliferation, and apoptosis. It has also been shown to be regulated by hypoxia. Loss of DEC1 expression may be an early event in lung cancer development, while DEC1 may be up‑regulated by hypoxia in other cancers and may play a role in cell death under extreme hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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