Thermo Fisher Scientific Phospho-PKC mu (Ser910) Polyclonal Antibody
PKD1/PKC mu의 Ser910 인산화 부위를 인식하는 rabbit polyclonal antibody. Western blot에 적합하며, 인산화된 PKD1/PKC mu의 내인성 수준을 특이적으로 검출. 액상 형태로 제공되며, -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PKD1/PKC mu around the phosphorylation site of Ser910 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899260 |
Product Specific Information
This antibody detects endogenous levels of PKD1/PKC mu only when phosphorylated at Ser910.
Target Information
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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