Thermo Fisher Scientific TERT Polyclonal Antibody
Hydra TERT 항원을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. Telomerase reverse transcriptase 연구용으로 적합하며, 동결건조 형태로 제공. 4°C 단기 보관, 장기 보관 시 -20°C 권장.
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- OST00410W-100UL
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cnidarian |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 600–650 of hydra TERT conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TERT.
Target Information
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by adding the telomere repeat TTAGGG.
The enzyme consists of a protein component with reverse transcriptase activity (encoded by the TERT gene) and an RNA component serving as a template.
Telomerase expression is typically repressed in postnatal somatic cells, leading to progressive telomere shortening and cellular senescence.
Deregulation of telomerase expression may contribute to oncogenesis.
Studies in mouse suggest telomerase also participates in chromosomal repair via de novo synthesis of telomere repeats at double-stranded breaks.
Alternatively spliced variants encoding different isoforms of TERT have been identified; some full-length sequences remain undetermined.
Alternative splicing is thought to regulate telomerase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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