Thermo Fisher Scientific ADAMTS1 Monoclonal Antibody (OTI4H2), TrueMAB
ADAMTS1 단백질을 인식하는 Mouse Monoclonal Antibody. Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer 및 trehalose 함유, -20°C 보관. 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 412–644 of human ADAMTS1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ADAMTS-1 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family.
Members share several distinct domains, including:
- Propeptide region
- Metalloproteinase domain
- Disintegrin-like domain
- Thrombospondin type 1 (TS) motif
ADAMTS-1 contains two disintegrin loops and three C-terminal TS motifs and exhibits anti-angiogenic activity.
Its expression is associated with inflammatory processes and cancer cachexia, and it is necessary for normal growth, fertility, and organ morphology/function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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