Thermo Fisher Scientific Fumarase Polyclonal Antibody
Fumarase 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, Flow Cytometry에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 연구용으로만 사용.
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- PA5116455
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human FH aa 83–267 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2901087 |
Product Specific Information
Positive controls: K562 cell lysates, LOVO, SiHa, rat testis tissue, human liver tissue, human liver carcinoma tissue, mouse colon tissue, HCT116.
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle (Krebs cycle) and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and N-terminal extended forms, differing by the translation start site. The mitochondrial form is generated by removal of the N-terminal extension. It functions as a homotetramer and is similar to thermostable class II fumarases. Mutations in this gene can cause fumarase deficiency leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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