Thermo Fisher Scientific Human IL21R Synthetic Peptide
인간 IL-21 수용체의 N-말단 13 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-19983과 함께 블로킹 펩타이드로 사용 가능합니다. IL-21 신호전달 연구 및 면역세포 기능 연구에 적합합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PEP0107
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids at the amino terminus of human IL-21 Receptor.
PEP-0107 can be used as a blocking peptide with polyclonal antibody PA5-19983.
Target Information
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptor family and forms a heterodimeric receptor complex with the common gamma-chain, which is also shared by receptors for IL-2 and IL-5.
This receptor mediates IL-21–dependent signaling, promoting proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. Ligand binding activates downstream signaling molecules including JAK1, JAK3, STAT1, and STAT3.
Knockout studies in mice suggest a role in immunoglobulin regulation. Three alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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