
Thermo Fisher Scientific B19 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:1,000
Immunohistochemistry (IHC)
1:50-1:250
ELISA (ELISA)
1:10,000
Immunoprecipitation (IP)
1:50-1:250
Product Specifications
Species Reactivity
Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 650-714 on mouse Hormonally Up-regulated Neu tumor-associated Kinase. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
HUNK,
uniProtId:
O88866-1,
ncbiNodeId:
10090,
antigenRange:
650-714,
antigenLength:
714,
antigenImageFileName:
HUNK-101AP_HUNK_O88866-1_Rabbit.svg,
antigenImageFileNamePDP:
HUNK-101AP_HUNK_O88866-1_Rabbit_PDP.jpeg,
sortOrder:
2}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
HUNK serine/threonine kinase or hormonally up-regulated Neu-associated kinase is a member of the mitogen-activated protein kinase family which is essential for mammary tumor metastasis. HUNK deletion in mice did not alter viability, fertility, longevity, or propensity to develop tumors and it is also dispensable for murine development. HUNK has been shown to participate in vesicular transport. Additionally, functional studies in mice suggest that HUNK regulates endocytosis via interaction with rabaptin-5 protein and induces changes in mammary glands during pregnancy. HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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